What is Butalbital, Acetaminophen and Caffeine?
Butalbital is in a group of drugs called barbiturates. It relaxes muscle contractions involved in a tension headache.
Acetaminophen is a pain reliever and fever reducer.
Caffeine is a central nervous system stimulant. It relaxes muscle contractions in blood vessels to improve blood flow.
Acetaminophen, butalbital, and caffeine is a combination medicine used to treat tension headaches that are caused by muscle contractions.
Acetaminophen, butalbital, and caffeine may also be used for purposes not listed in this medication guide.
NDCs and labelers of “Butalbital, Acetaminophen and Caffeine”
| NDC | Trade Name | Labeler Name | Deleted | Deleted Date |
|---|---|---|---|---|
| 50090-2105 | Butalbital, Acetaminophen and Caffeine | A-S Medication Solutions | YES | No later than 2023-03-29 |
| 54569-2538 | Butalbital, Acetaminophen and Caffeine | A-S Medication Solutions LLC | YES | No later than 2017-06-30 |
| 68084-0396 | Butalbital, Acetaminophen and Caffeine | American Health Packaging | YES | 2024-03-31 |
| 60687-0672 | Butalbital, Acetaminophen and Caffeine | American Health Packaging | NO | |
| 71610-0042 | butalbital, acetaminophen and caffeine | Aphena Pharma Solutions – Tennessee, LLC | YES | No later than 2020-04-01 |
| 67544-0394 | Butalbital, Acetaminophen and Caffeine | Aphena Pharma Solutions – Tennessee, LLC | YES | No later than 2020-04-01 |
| 17856-1787 | Butalbital, Acetaminophen and Caffeine | Atlantic Biologicals Corps | YES | No later than 2019-12-28 |
| 13107-0075 | Butalbital, Acetaminophen and Caffeine | Aurolife Pharma, LLC | YES | No later than 2023-03-29 |
| 69189-2544 | Butalbital, Acetaminophen and Caffeine | Avera McKennan Hospital | YES | No later than 2018-06-28 |
| 50268-0139 | Butalbital, Acetaminophen and Caffeine | AvPAK | YES | No later than 2019-12-28 |
| 71335-9603 | Butalbital, Acetaminophen and Caffeine | Bryant Ranch Prepack | NO | |
| 63629-2372 | BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | Bryant Ranch Prepack | NO | |
| 63629-1774 | Butalbital, Acetaminophen and Caffeine | Bryant Ranch Prepack | YES | 2024-03-31 |
| 71335-1977 | Butalbital, Acetaminophen and Caffeine | Bryant Ranch Prepack | YES | No later than 2024-03-26 |
| 63629-2087 | butalbital, acetaminophen and caffeine | Bryant Ranch Prepack | NO | |
| 71335-0347 | butalbital, acetaminophen and caffeine | Bryant Ranch Prepack | YES | No later than 2024-03-26 |
| 63629-2151 | Butalbital, Acetaminophen and Caffeine | Bryant Ranch Prepack | YES | 2024-03-31 |
| 63629-2140 | Butalbital, Acetaminophen and Caffeine | Bryant Ranch Prepack | YES | 2024-03-31 |
| 72162-1096 | butalbital, acetaminophen and caffeine | Bryant Ranch Prepack | NO | |
| 71335-2272 | Butalbital, Acetaminophen and Caffeine | Bryant Ranch Prepack | NO | |
| 71335-2270 | Butalbital, Acetaminophen and Caffeine | Bryant Ranch Prepack | NO | |
| 72162-1232 | BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | Bryant Ranch Prepack | NO | |
| 55154-2073 | BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | Cardinal Health | YES | No later than 2018-03-29 |
| 55154-0832 | Butalbital, Acetaminophen and Caffeine | Cardinal Health | YES | No later than 2017-12-29 |
| 55154-7988 | Butalbital, Acetaminophen and Caffeine | Cardinal Health | YES | No later than 2020-12-31 |
| 55154-7147 | BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | Cardinal Health 107, LLC | NO | |
| 68151-1313 | Butalbital, Acetaminophen and Caffeine | Carilion Materials Management | YES | No later than 2019-12-28 |
| 62135-0751 | BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | Chartwell RX, LLC | NO | |
| 61919-0022 | BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | DIRECT RX | NO | |
| 51407-0200 | BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | Golden State Medical Supply | YES | No later than 2022-09-29 |
| 51407-0556 | Butalbital, Acetaminophen and Caffeine | Golden State Medical Supply, Inc. | NO | |
| 60429-0589 | butalbital, acetaminophen and caffeine | Golden State Medical Supply, Inc. | YES | 2024-10-31 |
| 70010-0149 | Butalbital, Acetaminophen and Caffeine | Granules Pharmaceuticals Inc. | NO | |
| 52959-0913 | Butalbital, Acetaminophen and Caffeine | H.J. Harkins Company, Inc. | YES | No later than 2019-12-28 |
| 00143-1787 | Butalbital, Acetaminophen and Caffeine | Hikma Pharmaceuticals USA Inc. | YES | 2021-03-31 |
| 00179-0137 | Butalbital, Acetaminophen and Caffeine | KAISER FOUNDATION HOSPITALS | YES | No later than 2019-03-18 |
| 68387-0520 | Butalbital, Acetaminophen and Caffeine | Keltman Pharmaceuticals Inc. | YES | No later than 2017-04-03 |
| 10702-0253 | Butalbital, Acetaminophen and Caffeine | KVK-Tech, Inc. | NO | |
| 35356-0862 | Butalbital, Acetaminophen and Caffeine | Lake Erie Medical DBA Quality Care Products LLC | YES | No later than 2017-12-29 |
| 00527-4094 | butalbital, acetaminophen and caffeine | Lannett Company, Inc. | NO | |
| 00904-6538 | Butalbital, Acetaminophen and Caffeine | Major Pharmaceuticals | YES | No later than 2020-12-31 |
| 10135-0628 | Butalbital, Acetaminophen and Caffeine | Marlex Pharmaceuticals Inc | YES | No later than 2019-12-28 |
| 51862-0540 | butalbital, acetaminophen and caffeine | Mayne Pharma | YES | 2025-03-31 |
| 51862-0542 | butalbital, acetaminophen and caffeine | Mayne Pharma | YES | 2022-12-31 |
| 51862-0179 | butalbital, acetaminophen and caffeine | Mayne Pharma | NO | |
| 46672-0059 | butalbital, acetaminophen and caffeine | Mikart, Inc. | YES | No later than 2014-06-30 |
| 46672-0228 | butalbital, acetaminophen and caffeine | Mikart, Inc. | YES | No later than 2017-04-03 |
| 46672-0053 | butalbital, acetaminophen and caffeine | Mikart, LLC | NO | |
| 46672-0633 | Butalbital, Acetaminophen and Caffeine | Mikart, LLC | YES | No later than 2020-12-31 |
| 66267-0039 | butalbital, acetaminophen and caffeine | NuCare Pharmaceuticals, Inc. | YES | No later than 2020-04-01 |
| 68071-2927 | Butalbital, Acetaminophen and Caffeine | NuCare Pharmaceuticals,Inc. | NO | |
| 68071-4657 | butalbital, acetaminophen and caffeine | NuCare Pharmaceuticals,Inc. | YES | No later than 2023-03-29 |
| 00603-2544 | Butalbital, Acetaminophen and Caffeine | Par Pharmaceutical, Inc. | YES | 2024-03-31 |
| 55289-0879 | Butalbital, Acetaminophen and Caffeine | PD-Rx Pharmaceuticals, Inc. | YES | No later than 2020-12-31 |
| 43063-0369 | Butalbital, Acetaminophen and Caffeine | PD-Rx Pharmaceuticals, Inc. | YES | No later than 2020-04-01 |
| 54868-1036 | Butalbital, Acetaminophen and Caffeine | Physicians Total Care, Inc. | YES | No later than 2018-10-01 |
| 54868-5943 | Butalbital, Acetaminophen and Caffeine | Physicians Total Care, Inc. | YES | No later than 2014-03-31 |
| 68788-9025 | Butalbital, Acetaminophen and Caffeine | Preferred Pharmaceuticals, Inc. | YES | No later than 2020-04-01 |
| 68788-9711 | butalbital, acetaminophen and caffeine | Preferred Pharmaceuticals, Inc. | YES | No later than 2020-04-01 |
| 71205-0962 | Butalbital, Acetaminophen and Caffeine | Proficient Rx LP | NO | |
| 63187-0520 | butalbital, acetaminophen and caffeine | Proficient Rx LP | NO | |
| 00603-2545 | Butalbital, Acetaminophen and Caffeine | Qualitest Pharmaceuticals | YES | No later than 2014-03-31 |
| 21695-0843 | Butalbital, Acetaminophen and Caffeine | Rebel Distributors Corp | YES | No later than 2019-12-28 |
| 42254-0323 | Butalbital, Acetaminophen and Caffeine | Rebel Distributors Corp | YES | No later than 2019-12-28 |
| 21695-0257 | Butalbital, Acetaminophen and Caffeine | Rebel Distributors Corp. | YES | No later than 2019-12-28 |
| 67296-0718 | Butalbital, Acetaminophen and Caffeine | RedPharm Drug Inc. | YES | No later than 2019-12-28 |
| 52125-0274 | butalbital, acetaminophen and caffeine | REMEDYREPACK INC. | YES | No later than 2017-04-03 |
| 70518-3858 | Butalbital, Acetaminophen and Caffeine | REMEDYREPACK INC. | NO | |
| 52125-0275 | Butalbital, Acetaminophen and Caffeine | REMEDYREPACK INC. | YES | No later than 2017-04-03 |
| 52125-0276 | Butalbital, Acetaminophen and Caffeine | REMEDYREPACK INC. | YES | No later than 2017-04-03 |
| 61786-0365 | butalbital, acetaminophen and caffeine | REMEDYREPACK INC. | YES | No later than 2019-03-18 |
| 13925-0536 | BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | Seton Pharmaceuticals LLC | NO | |
| 13925-0535 | BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | Seton Pharmaceuticals LLC | NO | |
| 43547-0686 | BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | SOLCO HEALTHCARE US, LLC | NO | |
| 64380-0157 | Butalbital, Acetaminophen and Caffeine | Strides Pharma Science Limited | YES | No later than 2024-03-26 |
| 11534-0187 | BUTALBITAL, ACETAMINOPHEN AND CAFFEINE | SUNRISE PHARMACEUTICAL, INC | NO | |
| 51672-4222 | Butalbital, Acetaminophen and Caffeine | Taro Pharmaceuticals U.S.A., Inc. | YES | No later than 2024-03-26 |
| 50436-4856 | butalbital, acetaminophen and caffeine | Unit Dose Services | YES | No later than 2020-04-01 |
| 68453-0170 | Butalbital, Acetaminophen and Caffeine | Victory Pharmaceutical | YES | No later than 2017-04-03 |
| 42195-0955 | Butalbital, Acetaminophen and Caffeine | Xspire Pharma, LLC | YES | No later than 2024-03-26 |
What should I avoid while taking acetaminophen, butalbital, and caffeine?
This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.
Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.
While you are taking this medication, avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice.
