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Who Can Not Take Fioricet ?

Posted in Fioricet

Fioricet is the most effective prescription for headache including tension headache, migraine headache and even cluster headache and neck pain.


Fioricet is a combination medication typically prescribed for tension headaches. It contains acetaminophen (paracetamol), butalbital, and caffeine. While generally considered safe for most people when taken as prescribed by a healthcare professional, there are certain individuals who should not take Fioricet or should use it with caution. These include:

  1. Individuals with liver disease: Fioricet contains acetaminophen, which can be harmful to the liver in high doses. People with liver disease should consult their healthcare provider before taking Fioricet or may need a dosage adjustment.
  2. Those with a history of alcohol or substance abuse: Fioricet contains butalbital, a barbiturate that has the potential for abuse. Individuals with a history of alcohol or substance abuse should be cautious when taking Fioricet and should use it only under the guidance of a healthcare provider.
  3. People with porphyria: Porphyria is a group of rare disorders that affect the nervous system or skin. Some forms of porphyria can be triggered by certain medications, including those containing barbiturates like butalbital. Therefore, individuals with porphyria should avoid Fioricet.
  4. Those with a history of allergic reactions to any of the ingredients in Fioricet: Fioricet contains acetaminophen, butalbital, and caffeine. People who have had allergic reactions to any of these ingredients should not take Fioricet.
  5. Pregnant or breastfeeding women: The safety of Fioricet during pregnancy and breastfeeding has not been established. It’s essential for pregnant or breastfeeding women to consult their healthcare provider before using Fioricet.
  6. Individuals with certain medical conditions: Fioricet may interact with certain medical conditions, such as respiratory depression, kidney disease, stomach/intestinal problems, and mental/mood disorders like depression. Therefore, individuals with these conditions should use Fioricet with caution and under the guidance of a healthcare provider.
  7. If you have taken an MAO inhibitor in the past 14 days, you can not use Fioricet. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.
  8. If you have high pressure, please only take Fioricet after you consulted your doctors.
See also  Fioricet Drug Interactions that You Should Know

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