In people with kidney and liver problems, colchicine can cause a life-threatening interaction when taken with certain other medicines. People with kidney and liver problems should talk with their health care professional before taking colchicine.
In rare cases, colchicine can cause muscle damage and blood disorders.
Taking more colchicine than prescribed can lead to overdose and death.
Increased risk of gout attack when first starting to take it
If you get a skin rash while taking allopurinol or febuxostat, call your health care professional right away.
In very rare cases, allopurinol and febuxostat can cause severe skin reactions that can be life threatening. Symptoms may include red, blistered, or peeling skin; red or sore eyes; fever; and sores in your throat, mouth, or nose.
Allopurinol and febuxostat may affect how well your liver works. These medicines can also cause liver damage. Signs of liver problems can include feeling tired and weak, nausea, vomiting, yellowed skin or eyes (jaundice), and dark-colored urine.
Increased risk of a gout attack when first starting to take it
If you get a skin rash while taking allopurinol or febuxostat, call your health care professional right away.
In very rare cases, allopurinol and febuxostat can cause severe skin reactions that can be life threatening. Symptoms may include red, blistered, or peeling skin; red or sore eyes; fever; and sores in your throat, mouth, or nose.
Allopurinol and febuxostat may affect how well your liver works. These medicines can also cause liver damage. Signs of liver problems can include feeling tired and weak, nausea, vomiting, yellowed skin or eyes (jaundice), and dark-colored urine.
