Category: Doxepi

This article will help you know about the side effects of Doxepin that you need to monitor carefully and call medical help in case of emergency.

Anticholinergic Effects

·         Constipation

·         Urinary retention

·         Blurred vision

·         Dry mouth

If the above side effects do not subside with regular therapy or become serious, your doctor may reduce the dosage of Doxepin.

CNS effects

Drowsiness is the most common side effect observed in patients. This effect disappears as the patient starts receiving the therapy. Other CNS side effects that do not occur quite often are

·         Hallucinations

·         Hypertension

·         Cardiovascular effects

·         Hypotension

·         Tachycardia

Allergic effects

·         Edema

·         Skin rash

·         Pruritus

·         Photosensitization

Hematologic

Eosinophillia is seen in a few patients. Occasional reports of depression of bone marrow are exhibited as purpura, leukpenia, thrombocytopenia, and agranulocytosis.

·         Endocrine

·         Raised libido

·         Gynecomastia (in males)

·         Testicular swelling

·         Enlargement of breasts

·         Galactorrhea (in females)

·         Increase or decrease in blood sugar levels

Gastrointestinal

·         Vomiting

·         Nausea

·         Taste disturbances

·         Indigestion

·         Diarrhea

·         Anorexia

Other side effects are

·         Dizziness

·         Weight gain

·         Chills

·         Weakness

·         Fatigue

·         Dizziness

·         Flushing

·         Alopecia

·         Jaundice

·         Angle closure glaucoma

·         Hyperpyrexia

·         Asthma

·         Sweating

·         Tinnitus

·         Headache

·          Mydriasis

Major side effects are

·         Stomach or abdominal pain

·         Bleeding gums

·         Canker sores

·         Chills

·         Chest pain

·         Blood in stools or urine

·         Convulsions

·         Dark urine

·         Decreased urine volume

·         Hoarseness or cough

·         Pale or cool skin

·         Cold sweats

·         Depression

·         Drooling

·         Breathing difficulty

·         Urinating difficulty

·         Dry, flushed skin

·         Fever

·         Irritability

·         Nightmares

·         Noisy breathing

·         Restlessness

·         Shuffling walk

·         Slurred speech

·         Vomiting blood

·         Yellow skin or eyes

·         Trembling, unsteadiness or problems with muscle coordination or control

·         Unusual bruising or bleeding

·         Stupor

·         Swollen glands

Common side effects are

·         Feeling tired, drowsy or dizzy

·         Vomiting, constipation, nausea

·         Blurred vision, dry mouth

·         Decreased interest in sex

·         Breast swelling in females and males

Frequency not known

·         Agitation

·         Insomnia

·         Sweating

·         Anxiety

·         Headache

·         Confusion, parenthesis

·         Sexual dysfunction

·         Skin rash

·         Lethargy, weakness, fatigue or sedation

Symptoms of overdose

·         Disturbed concentration

·         Clumsiness

·         Enlarged pupils

·         Muscle aches

·         Shivering

·         Sleepiness

·         Weight gain

·         Feeble or weak pulse

·         Low body temperature

·         Muscle weakness

·         Excessive unconsciousness

Occurrence not known

·         Heartburn

·         Diarrhea

·         Severe sunburn

·         Inability to have erection or keep erection

·         Loss in sexual drive, desire, ability or performance

·         Increased sexual drive, desire, ability or performance

·         Increased skin sensitivity to sunlight

·         Swollen testicles

·         Unexpected flow of milk from breasts

·         Weight loss

·         Discoloration or redness of skin

·         Gas in stomach

·         Change in taste

·         Hair thinning or hair loss