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Prednisone- An immunosuppressant and anti-inflammatory medication

Prednisone is a corticosteroid that prevents the flow of substances in the body that cause inflammation. It also overpowers the immune system. It is used as immunosuppressant or anti-inflammatory medication. Prednisone is helpful in treating various health ailments like skin conditions, lupus, arthritis, ulcerative colitis, psoriasis, breathing disorders and allergic disorders.

Important Information

Avoid taking Prednisone if there is a fungal infection anywhere in your body. Steroid medications can make your immune system weak, which makes your body get an infection easily. Stay away from those who have infections or are sick. Do not opt for a live vaccine when you are on Prednisone.

Do not stop Prednisone suddenly and speak to your doctor regarding change in dosage.

To ensure whether Prednisone is suitable for you or not, let your doctor know if you have the following

  • any health problems that leads to diarrhoea
  • kidney disease
  • live disease
  • tuberculosis
  • osteoporosis
  • glaucoma/cataracts
  • thyroid disorder
  • history of malaria
  • mental illness/depression
  • muscle disorder like myasthenia gravis
  • history of stomach bleeding
  •  diabetes

Using steroids for a long term can lead to osteoporosis (bone loss) particularly if you smoke, if you do not work out, do not take adequate amount of calcium or vitamin D through your diet or you have a family history of osteoporosis. Speak to your doctor to know about the risks associated with osteoporosis.

Dosing information

Normal Adult dose – Nephrotic Syndrome

Initial dose: 2mg/kg/per day (maximum dose-80mg per day) in split dose of 3-4 times per day until urine gets protein free 3 consecutive days (maximum: 28 days) with 1-1.5mg/kg/per dose to be given every alternate day for almost 4 weeks.

Normal Paediatric dose – Asthma

Below 1 year

Acute: 10mg to be taken orally after every 12 hours

Maintenance: 10mg to be taken orally every alternate day

1-4 years

Acute: 20mg to be taken orally after every 12 hours

Maintenance: 20mg to be taken orally every alternate day

5-12 years

Acute: 30mg to be taken orally after every 12 hours

Maintenance: 30mg to be taken orally every alternate day

Above- 12 years

Acute: 40 mg orally every 12 hours.
Maintenance: 40 mg orally every alternate day.


Prednisone and pregnancy

Use of Prednisone during pregnancy can cause birth defects or low birth weight especially if you use Prednisone during the first three months of pregnancy. Speak to your doctor if you get pregnant or planning to get pregnant.

Prednisone and breastfeeding

Prednisone can secret in breast milk and can harm your baby. So talk to your doctor if you are a lactating mother.


Side effects

  • eye pain, blurred vision
  • tarry or bloody stools
  • pancreatitis
  • low potassium
  • fast weight gain, breathlessness
  • extreme sadness or happiness, severe, depression, change in behaviour or personality, convulsions
  • extremely high BP

Common side effects

  • increased appetite, slow weight gain
  • slow healing of wound
  • increases sweating, acne, dry skin, discoloration or bruising
  • sleep problems
  • bloating, nausea and stomach pain
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