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Methylprednisolone- Treating different inflammatory conditions effectively

Methylprednisolone is a steroid that helps preventing the flow of substances in the body that cause inflammation. Methylprednisolone is used to treat different medical conditions like psoriasis, allergic disorders, lupus, arthritis, ulcerative colitis and conditions that can affect stomach, skin, lungs, eyes, blood cells and nervous system.

Important Information

Avoid using this medication if you have a fungal infection in your body. Before you use Methylprednisolone, discuss with your doctor about your medical conditions and other medication that you are using. There are several diseases that can be influenced by the use of steroid and many other drugs can interact with these steroids.

Methylprednisolone can make your immune system weak and your body tends to get an infection easily or it can make the existing infection worse. In case you have any infection or illness in the past couple of weeks or at present, tell your doctor without any hesitation.

Stay away from people who are having infections or are sick. Call your physician for preventive treatment if you come in contact with measles or chickenpox virus. Do not stop taking Methylprednisolone all of a sudden, talk to your doctor for dosage adjustments.

Let your doctor know if you have any of these health problems

  • encountered head injury recently
  • liver or kidney disease
  • blood pressure or heart disease
  • cataracts/glaucoma
  • thyroid disorder
  • tuberculosis
  • pinworms
  • epilepsy or seizures
  • if you use aspirin in high doses or on a daily basis
  • if you use oral medication for diabetes or insulin
  • high calcium levels in blood associated with cancer
  • mental illness or depression

Dosing Information

If you miss a dose of Methylprednisolone, you should seek medical help and in case of overdose, call poison control centre. An overdose of Methylprednisolone though doesn’t lead to any life threatening effects, still long term use of steroids or taking in high doses can lead to serious side effects like easy bruising, thinning skin, increased facial hair or acne, impotence or menstrual problems.

Normal Adult Dose – Allergic Rhinitis:

Acetate: 80 -120 mg intramuscular only.

Normal Adult Dose – Dermatologic Lesion:

Acetate: 40-120 mg intramuscular – weekly for 1-4 weeks.

Usual Adult Dose – Rheumatoid Arthritis:

Acetate: 40 -120 mg intramuscular- weekly
Large joints: 20-80 mg intraarticular
Medium joints: 10-40 mg intraarticular
Small joints: 4-10 mg intraarticular


Methylprednisolone and pregnancy

It is still known whether using Methylprednisolone during pregnancy can harm unborn baby or not. It is better to discuss with your doctor if you planning to become pregnant or you are pregnant.

Methylprednisolone and breastfeeding

There are still no evidences available that state whether using Methylprednisolone during breastfeeding is safe or not for the baby or whether the medication secretes in breast milk.

Side effects

  • eye pain, tunnel vision, blurred vision
  • unusual pain in back, leg or arm
  • changes in personality, unusual behaviour or thoughts, severe depression
  • breathlessness, fast weight gain, swelling
  • convulsions
  • tarry or bloody stools
  • low potassium

Common side effects

  • weakness or mild pain in muscles
  • headache
  • bloating or stomach discomfort
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