Nutritional interventions as adjunctive treatment for schizophrenia

Schizophrenia is a type of chronic condition that only affects the individual but the family also. As far society is concerned it causes a significant cost to the country’s economy. The condition affects 1% of the total world’s population still there are a few natural options. The major treatment for Schizophrenia is through anti-psychotic medication. Though this method is not efficient in managing the serious symptoms of this disorder and the related side effects are quite serious. A lot of studies have found that the change in physiological mechanism can be controlled through nutritional interventions in some cases suffering from schizophrenia. The study says in additional to psychotic medication, nutritional approach can be used as adjunctive treatment for treating schizophrenia.

Well, these nutritional interventions might not provide one in all solution, but they can help treating schizophrenia to some extent.

Benefits of nutritional supplements and oxidative stress

Oxidative stress happen when defense capacity of a particular organism fails to balance ROS (reactive oxygen species) and RNS (reactive nitrogen species)production as generated through normal oxidative metabolic process. In case of schizophrenia there is an increase in oxidative stress.

Vitamin E and C

Vitamins E and C are dietary oxidants (non-enzymatic), which can be effective in handling oxidative stress in people suffering from schizophrenia as they help breaking down chain reactions of free radicals. Vitamin E can help in preventing diskinesia (TD) deterioration and enhances TD. Therefore using Vitamin E supplements can help patients who experience distressing symptom.

Vitamin B and Folate Supplementation

Folate supplementation has helped individuals suffering from schizophrenia as it helped reducing the levels of homocysteine. Supplements of vitamin B12 also helped in decreasing the homcysteine levels.

Diet with anti-psychotic medication

Many studies have detected positive results by introducing a diet free of gluten for individuals suffering from schizophrenia along with standard health care. There was a lot of improvement shown in males who were given cereal and milk free diet. The patients who were kept on this diet were moved to open ward from locked ward for patients within minimum seven days as compared to other patients who were on milk-cereal diet.

Vitamin D was a risk factor in schizophrenia patients

It was found that vitamin D when given during pre natal care can alter the development of brain. In some cases, vitamin D in high doses increased the risk of having schizophrenia. Though a recent study also shows that sufficient amount of vitamin D is essential for the development of normal brain.

Schizophrenia is quite complex, devastating and disabling disorder which actually cannot be treated successfully using psychotic medication which is not efficient in treating this disorder. The side effects are severe and nutritional strategies can help to eradicate related side effects but cannot work towards curing it completely. Therefore to treat this disorder, personalized medicine plus nutritional interventions can be beneficial. Though it doesn’t affect many people, but still the studies and research needs to be done to find the solution for this complex disorder.

Nutritional Interventions for Diabetic People

The goal of medical nutrition therapy is to prevent, manage and slow the rate at which the complications of diabetes arise. The goal also includes making health care providers and diabetic people aware of effective nutritional interventions. To achieve this goal the necessities are using the best available medical and science evidence, while monitoring the treatment and make strategies to achieve the goal and changes that people suffering from diabetes are able to make or willing to make.

Nutritional Interventions – Specific population

For individuals having type 1 diabetes, insulin ideally should be incorporated into his/her physical or dietary activity pattern. Individuals who use rapid-acting dose of insulin through insulin pump or insulin injections should actually adjust their snack and meal insulin doses depending on carbohydrate content of snacks and meals.

For people who use fixed doses of insulin on a daily basis, carbohydrate intake on a daily basis should be consistent based on amount and time. If an individual has planned exercise, the doses of insulin can be easily adjusted. If the exercise is unplanned, there is a need of extra carbohydrate content.

The first priority of nutrition for people who require insulin therapy is to involve an insulin regimen into their daily lifestyle. Nowadays there are many options available for insulin and a right insulin regimen can be incorporated to a particular individual’s food choices, meal routine or pattern of their physical activity. In case of planned exercise, reducing insulin dosage is the common method adopted in order to prevent hypoglycemia.  In case of unplanned exercise one needs to take extra carbohydrate content. In case of intense activity more carbohydrate content is required.

Nutritional Interventions- for type2 diabetes

People having type 2 diabetes are recommended to execute lifestyle modifications, that helps reducing energy intake, cholesterol, trans fatty acids and saturated fats, sodium and also increase their physical activities in order to improve blood pressure, glycemia  and dyslipidemia.

Monitoring of Plasma glucose can be useful to consider if the adjustments in meals and foods are enough to achieve goals for blood glucose or medication is required in combination with MNT.

Nutrition recommendations for healthy lifestyle given for general public are also helpful for individuals suffering from type 2 diabetes. The reason that many people suffering from type 2 diabetes are insulin resistant and overweight, MNT should focus on certain changes in lifestyle that helps promote increased energy through one’s physical activity. The fact that many people also have hypertension, dyslipidemedia, decreasing sodium, cholesterol, and saturated fatty acids and trans fatty acids is essential. In this case the first priority o nutrition should be to motivate people suffering from type 2 diabetes to implement changes in lifestyle strategies that can help improve blood pressure, glycemia and dyslipidemia.

Increase in physical activity can help people with type 2 diabetes reduce the cardiovascular and overweight risks. So if you have anyone in your family suffering from diabetes you can help them know the importance of physical activity and how it can help them maintain blood sugar levels preventing the risks caused by diabetes.

Nutritional Interventions for children with Autism

Biomedical research recommends that supplements and food may affect children with autism, learning disabilities, sensory issues, attention concerns, social withdrawal, avoiding the eye-contact and perseverative behaviours. In specific, it might be attributable to the inability to break down specific food proteins to harm the developing brain of children. The foods which appear to create harm are gluten and casein. Several parents, nutritionists and doctors have reported great improvement in attention, behaviour and relatedness subsequent to eliminating foods comprising proteins from the child’s diet.

It is important to note that GF/CF diet assist 85% of children to improve the overall wellbeing of the child. This consist of speech, better movements of bowel, good sleep patterns, less irritable and stimmy behaviors, less in daze and fog look and always ready to attend.

Different kind of Nutritional diet

SCD diet – It is also known as Specific Carbohydrate diet that allows intestines to heal. However, only carbohydrates which can get digested easily are allowed to be consumed. No grains and no potatoes are allowed in this diet. Vegetables and Fruits should get peeled properly before being used. Nuts are also allowed in this diet but peanuts, may be moldy. Kids might have an allergy to specific nut.

Low Oxalate Diet – It is important to understand that Oxalate is highly reactive molecule which is available abundant in different plant foods. If Oxalate is found in extreme quantity in the human cells, it can lead to depletion of glutathione, oxidative damage and igniting inflammatory cascade of the immune system.

Soy – It is quite closely related with casein and phytoestrogens in soy that will put some additional load on PST enzyme.

MSG: It is also known as monosodium glutamate. The hydrolyzed vegetable protein and Modified Food Starch are very hard for a person who is subjected to the overgrowth of yeast.

Diet with Low Sugar – Many kids has a problem with overgrowth yeast. Sugar nourishes yeast and should be monitored or if required eliminated for your diet.

Issues in Food Chemistry: Phenols, Amines and Salicylates are chemicals that are found in all foods. Some children may also have difficulty to process the natural food chemicals in useful as well as non-harmful substances. Such kind of condition is known as PST deficiency.

Some specific symptoms that indicate your child might have a concern. The symptoms are under eyes dark circles, red ears and face, diarrhea, aggression, hyperactivity, headache, head banging as well as other self-injury, unsuitable laughter, difficulty in falling asleep during night, and while night waking for many hours.

Supplements which are beneficial: Probiotics are also living microorganisms which support the immune systems and healthy gastrointestinal.

Digestive enzymes help with the intolerances of food with poor digestion. The enzyme test will also reveal what child has trouble in digesting, absorbing as well as assimilating, like protein, fats and sugars plus specific nutritional deficiencies, like calcium and vitamin C.

Minerals and Vitamins for suitable Methyl Metabolism, Fatty Acids, Amino Acids, Antioxidants, Epsom Salt Baths and Herbs are other important regimes of natural supplemental to explore.


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