Consider the lowest effective dose of Toradol for maximum benefits

While using Toradol consider the risks and benefits of Toradol and other alternative treatment options before you decide to take Toradol. Use the lowest effective dose for short term that goes with the treatment goals of each individual. In adults, the duration of both IM and IV dosing of ketorolac tromethamine and Toradol should not be exceeded for more than 5 days.

Change from IM or IV dosing of ketorolac tromethamine (single/multiple dose) to multiple dose Toradol.

Patients in age group of 17-64 yrs

20mg PO given once followed by q4-10mg – 6 hours prn not more than 40 mg per day

Patients with age 65 or above, renally impaired having weight less than 50kg : 10mg PO given once followed by q4-10mg – 6 hours prn not more than 40 mg per day

Note

Avoid giving oral formulation as an initial dose

Minimum effective dose should be used for each patient

Do not reduce the dosing interval of 4-6 hours

Total treatment duration in adult patients:

The duration of use of both IM and IV dosing of ketorolac tromethamine and Toradol not exceeding 5 days

Dosing instructions

Age less than 17 years – oral not approved

Adult age 17-64 years

20 mg once, then 10mg q4- 6 hours prn not more than 40 mg per day

What if I miss a dose?

As Toradol is a pain medication, there are fewer chances that you miss a dose, but in case you miss a dose, skip the missed dose in case it is almost the time for your next dose. Avoid taking extra medicine to make up for the missed dose.

What if I overdose?

Seek help from poison control centre or your health care provider.

Toradol Overdose and treatment

Signs and symptoms of overdose

Symptoms related to overdose of NSAIDs are normally limited to nausea, vomiting, drowsiness, epigastric pain and lethargy, which can be treated with timely supportive care. Gastrointestinal bleeding can also occur. Respiratory depression, coma and acute renal failure are some rare symptoms. Anaphylactoid reactions have been observed with the use of NSAIDs and it can also lead to overdose

Treatment

Patients should be treated with supportive care and symptomatic care for a Toradol overdose. There are no particular antidotes available. Activated charcoal (60-100g in adults, 1g/kg – 2g/kg in children) or osmotic cathartic can be indicated in patients observed within 4 hours of drug ingestion with symptoms or in patients who overdose by taking large doses like 5-10 times than the normal dose.  Urine alkalization, hemoperfusion, hemodialysis or forced dieresis might not be helpful in some cases.

Single overdose of this medication is linked to nausea, abdominal pain, hyperventilation, vomiting, peptic ulcers, renal dysfunction, and erosive gastritis after stopping the dosage.

In case of overdose, medical help should be given to the patient as soon as possible so that the toxicity can be removed from patient’s body and the life threatening risks can be reversed. The effectiveness of treatment depends on the duration of drug ingestion and the amount of drug taken.

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