Trimipramine dosage information to get maximum benefits

Trimipramine should be taken as directed by your doctor. Do not change your Trimipramine dose on your own. Do not discontinue the medicine without your doctor’s consent. To get maximum benefits, it is necessary to take the recommended dosage. This article will help you learn about the right Trimipramine dosage information. Consult your health care provider for the right dosage as each case is different and depending upon your medical condition, the doctor can prescribe you the right dose.

Dosage should be started at low doses, which can be increased slowly as required, depending on the patient’s tolerance to the medicine and clinical response. Lower dosages are prescribed for adolescents and elderly patients. Lower dosages are also given to patients who are not being hospitalized as compared to the doses given to a patient who is hospitalized. It is not possible to prescribe a general single dose of Trimipramine maleate(capsules) that can act as an effective treatment method in all patients. Therefore the right dosage depends on various factors like patient’s age, severity and chronicity of the disease, level of psychotherapeutic support and medical condition of a particular patient.

Most antidepressants take a period of minimum 10days to 4 weeks to show positive results. Dosage increment can cut down this period, but would result in adverse reactions too.

Normal Adult Dose

Office patients/Outpatients

Initial Dose: 75mg/day in split doses, which can be increased to 150mg/day.

Dosages should not exceed 200mg/day

Maintenance therapy: 50-150mg/day

Hospitalized patients

Initial dose: 100mg/day in split doses. This can increase to 200/mg/day slowly in a couple of days, depending upon individual’s tolerance and response to the medication

If there is no improvement seen in patient in 2-3 weeks, the dose can be increased to maximum dose of 250-300mg/day

Geriatric and Adolescents patients

Initial Dose: 50mg/day is ideal, which can be increased gradually to 100mg/day depending upon individual’s tolerance and response to the medication

Trimipramine over dosage and treatment

Over dosages of this class of medications can even lead to death. Multiple drug ingestion is very common with antidepressant overdose. The overdose management is changing every day and is quite challenging. Keeping this factor in mind, one should call medical help or poison control centre immediately in case of Trimipramine over dose. Symptoms and signs of toxicity accelerate after overdose of Trimipramine and thus hospitalization is must for a patient.

Signs of Trimipramine overdose include:

  • vomiting
  • drowsiness
  • stupor
  • agitation
  • hypothermia
  • hyperactive reflexes
  • hyperpyrexia
  • dilated pupils
  • disturbed concentration
  • muscle rigidity
  • hallucinations

Treatment

To treat Trimipramine overdose, an ECG is obtained immediately followed by cardiac monitoring. Patient’s airway is secured, gastric decontamination is started and an intravenous line is established. The patient is kept under medical observation for at least 6 hours wherein cardiac monitoring is conducted to check for signs of hypotension, respiratory or CNS depression, seizures and cardiac dysrhythmias. If the toxicity signs continue during this period, the monitoring is extended for some more time.

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